Head of Biology

During the coming years, we will take our Her2-directed antibody-drug conjugate LxC-001 to the clinic, and our liver disease-directed conjugates through the preclinical development stage. On this cutting edge of disease-specific biologicals development, we are searching for a Head of Biology.

July 25, 2019

As Head of Biology, you will play a key role in steering and supporting the development of our products from the biological perspective. Your responsibilities will range from developing cell-based in vitro assays, to outlining and overseeing complex IND-enabling non-clinical studies. More specifically, you will:

  • Lead the LinXis biology team.
  • Develop (bio-)assays and preclinical models that support LinXis products throughout discovery and development.
  • Support the design and execution of complex biological (in vivo) studies to assess fate, safety and efficacy of LinXis products (PKPD/ADME, drug targeting, response assessment, toxicology).
  • Support the development of the biological targeting moieties (e.g. antibodies) that are used as the targeting moieties of LinXis products.
  • Support non-clinical and clinical development with respect to bio-analytics (PKPD, ADME) and biomarkers.

To qualify for this position, we expect you to have:

  • A PhD in a life science- related biological field.
  • At least 10 years experience in biological therapeutics or targeted therapy, preferably in the areas of oncology or liver disease, and in an industrial setting.
  • A sound grasp of pathobiology from the molecular scale to the cellular-, animal- and human scale.
  • Hands-on experience in in vivo studies.
  • Experience in working in cross-functional research- and development teams.

What we offer:

We offer a unique career opportunity under attractive conditions. The small size and early stage of LinXis guarantees a dynamic and challenging work environment, and provides substantial possibility for personal growth. Flexibility and a hands-on mentality will be your most valuable assets. If you are up to the challenge of helping us make the difference, please send your resume and letter of motivation to careers@linxispharmaceuticals.com. You will work in both our Amsterdam as well as our Utrecht locations.