Head of Biology

During the coming years, we will take our Her2-directed antibody-drug conjugate LxC-001 to the clinic, and our liver disease-directed conjugates through the preclinical development stage. On this cutting edge of disease-specific biologicals development, we are searching for a Head of Biology.

July 25, 2019

As Head of Biology, you will play a key role in steering and supporting the development of our products from the biological perspective. Your responsibilities will range from developing cell-based in vitro assays, to outlining and overseeing complex IND-enabling non-clinical studies. More specifically, you will:

  • Lead the LinXis biology team.
  • Develop (bio-)assays and preclinical models that support LinXis products throughout discovery and development.
  • Support the design and execution of complex biological (in vivo) studies to assess fate, safety and efficacy of LinXis products (PKPD/ADME, drug targeting, response assessment, toxicology).
  • Support the development of the biological targeting moieties (e.g. antibodies) that are used as the targeting moieties of LinXis products.
  • Support non-clinical and clinical development with respect to bio-analytics (PKPD, ADME) and biomarkers.

To qualify for this position, we expect you to have:

  • A PhD in a life science- related biological field.
  • At least 10 years experience in biological therapeutics or targeted therapy, preferably in the areas of oncology or liver disease, and in an industrial setting.
  • A sound grasp of pathobiology from the molecular scale to the cellular-, animal- and human scale.
  • Hands-on experience in in vivo studies.
  • Experience in working in cross-functional research- and development teams.

What we offer:

We offer a unique career opportunity under attractive conditions. The small size and early stage of LinXis guarantees a dynamic and challenging work environment, and provides substantial possibility for personal growth. Flexibility and a hands-on mentality will be your most valuable assets. If you are up to the challenge of helping us make the difference, please send your resume and letter of motivation to You will work in both our Amsterdam as well as our Utrecht locations.