Partnering with CMOs

LinXis offers Lx®-payload semifinal products, cGMP produced, for use in your contract manufacturing of ADCs:

  • Lx®-payload semifinal products are water soluble, are stable and can be stored
  • LinXis can provide semifinal products with the payload of your choice
  • Lx®-payload conjugation is a robust, one-step reaction in buffered aqueous solutions under mild reaction conditions
  • No need for mAb modification (no tag introduction or mild reduction)
  • With a conjugation result that is reproducible and has a narrow DAR range, due to the conjugation to histidines in the mAb’s Fc region
  • Resulting in a stable and robust ADC with a high efficacy and a large therapeutic window

For other advantages, see the technology section.
If you are interested and want to discuss possibilities for cooperation with LinXis, please contact Gerro van Rheenen.